Endocrine Abstracts

Thyrotropin-secreting pituitary adenomas (TSHomas) are rare functioning pituitary adenomas, accounting for less than 1%. They commonly present as macroadenomas with symptoms of hyperthyroidism. Though surgery is the first line therapy, cure is achieved in only 30–40%, with high rate of post-surgical hypopituitarism. We propose somatostatin analogs having a new role in the management. We report a case of 73 years-old man with a 6-month history of palpitations and progress...

Introduction: Bilateral adrenal hemorrhage (BAH) is a rare clinical condition (estimated incidence between 0.14% –1.8%, according to postmortem studies) and life-threatening due to the development of adrenal crisis, after the destruction of 90% of each adrenal gland. A mortality rate of 15% has been reported despite treatment, but it depends on the severity of the underlying condition, reaching 90% in cases of sepsis, or even higher if it is not diagnosed quickly enough....

ObjectiveSurgery is the only curative treatment for primary hyperparathyroidism. Minimally invasive parathyroidectomy is superior in terms of cure and complication rates and is less costly than inpatient bilateral cervical exploration. Preoperative localization of parathyroid adenoma by imaging is a requirement for outpatient minimally invasive surgery. One of the most frequently used imaging techniques for parathyroid adenoma localization is Tc99m-sesta...

Introduction: Growth hormone deficiency (GHD) is associated with worsening body composition and growth hormone replacement therapy (GHRT) has shown to improve it in several studies. The objectives of this study were to evaluate the effects of long-term GHRT on body composition in adult patients with GHD andassess, in this population, the agreement between two different methods to measure fat mass that are total body fat mass (FM) and relative fat mass (RFM).<p class="abste...

IntroductionAcromegaly is an uncommon chronic disease with an insidious course. Due to the high morbimortality it causes, its early diagnosis and treatment are priority. The three therapeutic pillars are surgery, pharmacological treatment and radiotherapy, alone or in combination.ObjectivesTo clinically, biochemically and histologically characterize patients with acromegaly under follow-up in a tertiary hospi...

Purpose: To evaluate differences in the prevalence of autonomous cortisol secretion (ACS) and related comorbidities between patients with unilateral and bilateral adrenal incidentalomas (AI).Methods: Seven Spanish institutions participated in this institutional review board-approved retrospective study for patients with AI. 342 patients with one or more AI ≥ 1 cm evaluated by participating physicians between 2001 and 2019 were subject to inclusion....